Tg(Pou4f1-cre/ERT2)2Jiz
Transgene Detail

Summary

• Symbol: Tg(Pou4f1-cre/ERT2)2Jiz
• Name: transgene insertion 2, Jian Zhong
• MGI ID: MGI:5619669
• Synonyms: brn3a-CreER^T2
• Transgene: Tg(Pou4f1-cre/ERT2)2Jiz Location: unknown
• Alliance: Tg(Pou4f1-cre/ERT2)2Jiz page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Pou4f1-cre/ERT2)2Jiz expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Pou4f1 (MGI:102525)

• Mutation details: The mouse gene main transcription enhancer (11kb) drives DRG neuron-specific expression of the cre/ERT2 fusion. (J:213126)

Schematic of the Tg(Pou4f1-cre/ERT2)2Jiz transgene

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Pou4f1 (mouse) Summary of all recombinase alleles driven by Pou4f1. Comparative matrix view of recombinase activities Alliance mouse Pou4f1 gene page

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:213126 O'Donovan KJ, et al., B-RAF kinase drives developmental axon growth and promotes axon regeneration in the injured mature CNS. J Exp Med. 2014 May 5;211(5):801-14
• All: 9 reference(s)