Tg(Grem1-cre/ERT)3Tcw
Transgene Detail

Summary

• Symbol: Tg(Grem1-cre/ERT)3Tcw
• Name: transgene insertion 3, Timothy C Wang
• MGI ID: MGI:5620176
• Synonyms: Grem1-creER^T
• Transgene: Tg(Grem1-cre/ERT)3Tcw Location: unknown
• Alliance: Tg(Grem1-cre/ERT)3Tcw page

Transgene origin

• Strain of Origin: C57BL/6 x CBA

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Grem1-cre/ERT)3Tcw expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Grem1 (MGI:1344337)

• Mutation details: The mouse bacterial artificial chromosome (BAC) RP24-317C19 containing the Grem1 gene, was modified by insertion of a creERT coding sequence. DNA from a creERT modified BAC clone was used as the source for the transgene. Founder line 3 was subsequently established. (J:219328)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Grem1 (mouse) Summary of all recombinase alleles driven by Grem1. Comparative matrix view of recombinase activities Alliance mouse Grem1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:219328 Worthley DL, et al., Gremlin 1 identifies a skeletal stem cell with bone, cartilage, and reticular stromal potential. Cell. 2015 Jan 15;160(1-2):269-84
• All: 6 reference(s)