Nus1^tm1Wcsa
Targeted Allele Detail

Summary

• Symbol: Nus1^tm1Wcsa
• Name: NUS1 dehydrodolichyl diphosphate synthase subunit; targeted mutation 1, William C Sessa
• MGI ID: MGI:5620526
• Synonyms: NgBR^f
• Gene: Nus1 Location: Chr10:52293643-52316279 bp, + strand Genetic Position: Chr10, 26.64 cM
• Alliance: Nus1^tm1Wcsa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:215785
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 1. A neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 1. (J:215785)

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nus1 Mutation: 19 strains or lines available

References

• Original: J:215785 Park EJ, et al., Mutation of Nogo-B receptor, a subunit of cis-prenyltransferase, causes a congenital disorder of glycosylation. Cell Metab. 2014 Sep 2;20(3):448-57
• All: 2 reference(s)