Tg(Fev-cre)FF3Pasq
Transgene Detail

Summary

• Symbol: Tg(Fev-cre)FF3Pasq
• Name: transgene insertion FF3, Massimo Pasqualetti
• MGI ID: MGI:5620669
• Synonyms: Pet1210-Cre
• Transgene: Tg(Fev-cre)FF3Pasq Location: unknown
• Alliance: Tg(Fev-cre)FF3Pasq page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Fev-cre)FF3Pasq expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Fev (MGI:2449712)

• Mutation details: The transgene is composed of the RP23_165_D11 BAC with the cre recombinase gene inserted at the translation start site of the 210 kb Fev fragment followed by an FRT-flanked neomycin resistance cassette. Flp-mediated recombination removed the selection cassette. Passenger genes in the BAC include Cdk5r2, Cryba2, Ccdc108, Ihh and Nhej1. Founder FF3, FF9 and FM3 were generated. (J:218991)

Schematic of the Tg(Fev-cre)FF3Pasq, Tg(Fev-cre)FF9Pasq, Tg(Fev-cre)FM3Pasq and MGI:5620672 transgenes

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Fev (mouse) Summary of all recombinase alleles driven by Fev. Comparative matrix view of recombinase activities Alliance mouse Fev gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:218991 Pelosi B, et al., Generation of Pet1210-Cre transgenic mouse line reveals non-serotonergic expression domains of Pet1 both in CNS and periphery. PLoS One. 2014;9(8):e104318
• All: 2 reference(s)