Npr3^skm1
Chemically induced Allele Detail

Summary

• Symbol: Npr3^skm1
• Name: natriuretic peptide receptor 3; skeletal morphology mutant 1
• MGI ID: MGI:5620887
• Gene: Npr3 Location: Chr15:11839982-11907287 bp, - strand Genetic Position: Chr15, 5.83 cM
• Alliance: Npr3^skm1 page

Mutation origin

• Strain of Origin: 129S1/SvImJ

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a T-to-A transversion that results in the amino acid substitution of isoleucine with asparagine at position 384 (p.I384N). (J:218364)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Npr3 Mutation: 50 strains or lines available

References

• Original: J:218364 Dauphinee SM, et al., Characterization of two ENU-induced mutations affecting mouse skeletal morphology. G3 (Bethesda). 2013 Oct;3(10):1753-8
• All: 1 reference(s)