Esrrg^tm1Sjda
Targeted Allele Detail

Summary

• Symbol: Esrrg^tm1Sjda
• Name: estrogen-related receptor gamma; targeted mutation 1, Sally J Dawson
• MGI ID: MGI:5620890
• Gene: Esrrg Location: Chr1:187340988-187947082 bp, + strand Genetic Position: Chr1, 91.83 cM, cytoband H5
• Alliance: Esrrg^tm1Sjda page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:211740
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A lacZ and a neomycin selection cassette were inserted in exon 2 so that the lacZ start codon replace that of the endogenous gene. No mRNA transcript or protein was detected in targeted mice. (J:211740)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Esrrg Mutation: 32 strains or lines available

References

• Original: J:211740 Nolan LS, et al., Estrogen-related receptor gamma and hearing function: evidence of a role in humans and mice. Neurobiol Aging. 2013 Aug;34(8):2077.e1-9
• All: 1 reference(s)