Tg(Crx-AIPL1*P351)#Visu
Transgene Detail

Summary

• Symbol: Tg(Crx-AIPL1*P351)#Visu
• Name: transgene insertion, Visvanathan Ramamurthy
• MGI ID: MGI:5621018
• Synonyms: P351delta12 hAIPL1
• Transgene: Tg(Crx-AIPL1*P351)#Visu Location: unknown
• Alliance: Tg(Crx-AIPL1*P351)#Visu page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(Crx-AIPL1*P351)#Visu expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  AIPL1 (23746)

  Aipl1

  (MGI:2148800)

• Mutation details: This transgene expresses the human AIPL1 with a 12 bp, 4 amino acid residue in-frame deletion in the C-terminal proline-rich region with an N-terminal Flag tag under the control of a 2.3 kb mouse Crx promoter. The pound symbol (#) is used when line is not specified. (J:218096)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:218096 Ku CA, et al., Viral-mediated vision rescue of a novel AIPL1 cone-rod dystrophy model. Hum Mol Genet. 2015 Feb 1;24(3):670-84
• All: 1 reference(s)