Kcnq2^tm1Snhr
Targeted Allele Detail

Summary

• Symbol: Kcnq2^tm1Snhr
• Name: potassium voltage-gated channel, subfamily Q, member 2; targeted mutation 1, Shinichi Hirose
• MGI ID: MGI:5629427
• Gene: Kcnq2 Location: Chr2:180717372-180777093 bp, - strand Genetic Position: Chr2, 103.57 cM, cytoband H3-4

Mutation origin

• Germline Transmission: Unknown
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

Allele Type: Targeted (RMCE-ready) Mutation: Insertion Mutation details: A lox71 site was inserted upstream of exon 6. An FRT-flanked neomycin resistance cassette with an internal lox2272 site was inserted downstream of exon 6. (J:213443)

Generation of the Kcnq2^tm1Snhr, Kcnq2^tm2.1Snhr, and Kcnq2^tm3.1Snhr alleles

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kcnq2 Mutation: 50 strains or lines available

References

• Original: J:213443 Tomonoh Y, et al., The kick-in system: a novel rapid knock-in strategy. PLoS One. 2014;9(2):e88549
• All: 1 reference(s)