Dpep3^{tm1(EGFP/cre/ERT2)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Dpep3^{tm1(EGFP/cre/ERT2)Wtsi}
• Name: dipeptidase 3; targeted mutation 1, Wellcome Trust Sanger Institute
• MGI ID: MGI:5629520
• Synonyms: Dpep3^{tm1(cre/ERT2)Hmgu}
• Gene: Dpep3 Location: Chr8:106700152-106706051 bp, - strand Genetic Position: Chr8, 53.07 cM
• Alliance: Dpep3^{tm1(EGFP/cre/ERT2)Wtsi} page

Mutation origin

• Mutant Cell Line: CEPD0067_2_E07
• Germline Transmission: Earliest citation of germline transmission: J:188991
• Parent Cell Line: JM8.N4 (ES Cell)
• Strain of Origin: C57BL/6N
• Project Collection: EUCOMMTOOLS

Mutation description

• Allele Type: Targeted (Conditional ready, Inducible, Recombinase, Reporter)
• Inducer: tamoxifen
• Mutation: Insertion
• Dpep3^{tm1(EGFP/cre/ERT2)Wtsi} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Dpep3 (MGI:1919104)

• Mutation details: According to the cassette image presented by the International Knockout Mouse Consortium this allele has a loxP site downstream of exon 7 and just upstream of exon 3 and inserted into the intron between exons 2 and 3 is one FRT site, an engrailed 2 splice acceptor sequence, an EGFP, cre/ERT2 cassette, then a Rox flanked puromycin resistance cassette. (J:155845)
• Inheritance: Not Specified

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Dpep3 (mouse) Summary of all recombinase alleles driven by Dpep3. Comparative matrix view of recombinase activities Alliance mouse Dpep3 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dpep3 Mutation: 22 strains or lines available

References

• Original: J:155845 Wellcome Trust Sanger Institute, Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2010
• All: 2 reference(s)