Asb4^tm1.2Cpat
Targeted Allele Detail

Summary

• Symbol: Asb4^tm1.2Cpat
• Name: ankyrin repeat and SOCS box-containing 4; targeted mutation 1.2, Cam Patterson
• MGI ID: MGI:5629538
• Gene: Asb4 Location: Chr6:5383386-5433022 bp, + strand Genetic Position: Chr6, 1.99 cM
• Alliance: Asb4^tm1.2Cpat page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:213825
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Cre-mediated recombination removed exon 1. This allele lacks the FRT-flanked neomycin resistance cassette inserted upstream of exon 1. (J:213825)

Disease models

Expression

In Structures Affected by this Mutation:

7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Asb4 Mutation: 30 strains or lines available

References

• Original: J:213825 Townley-Tilson WH, et al., The ubiquitin ligase ASB4 promotes trophoblast differentiation through the degradation of ID2. PLoS One. 2014;9(2):e89451
• All: 2 reference(s)