Oma1^tm1Tlan
Targeted Allele Detail

Summary

• Symbol: Oma1^tm1Tlan
• Name: OMA1 zinc metallopeptidase; targeted mutation 1, Thomas Langer
• MGI ID: MGI:5629810
• Synonyms: Oma1^loxP
• Gene: Oma1 Location: Chr4:103171009-103229065 bp, + strand Genetic Position: Chr4, 47.6 cM, cytoband C6
• Alliance: Oma1^tm1Tlan page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:215813
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exon 3 was floxed and a frt-flanked neo cassette upstream of exon 3 was removed via Flp-mediated recombination. (J:215813, J:229455)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Oma1 Mutation: 23 strains or lines available

References

• Original: J:215813 Anand R, et al., The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission. J Cell Biol. 2014 Mar 17;204(6):919-29
• All: 5 reference(s)