Cpne6^{tm1.1(EGFP/cre/ERT2)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Cpne6^{tm1.1(EGFP/cre/ERT2)Wtsi}
• Name: copine VI; targeted mutation 1.1, Wellcome Trust Sanger Institute
• MGI ID: MGI:5632472
• Synonyms: Cpne6^{tm1.1(EGFP/cre/ERT2)Hmgu}
• Gene: Cpne6 Location: Chr14:55747902-55754888 bp, + strand Genetic Position: Chr14, 28.19 cM
• Alliance: Cpne6^{tm1.1(EGFP/cre/ERT2)Wtsi} page

Mutation origin

• Mutant Cell Line: CEPD0017_6_C04
• Germline Transmission: Earliest citation of germline transmission: J:204812
• Parent Cell Line: JM8.N4 (ES Cell)
• Strain of Origin: C57BL/6N
• Project Collection: EUCOMMTOOLS

Mutation description

• Allele Type: Targeted (Inducible, Recombinase, Reporter)
• Inducer: tamoxifen
• Mutation: Insertion
• Cpne6^{tm1.1(EGFP/cre/ERT2)Wtsi} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Cpne6 (MGI:1334445)

• Mutation details: According to the allele molecular image presented by the International Knockout Mouse Consortium, this allele has exons 4 through 13 removed, and inserted into the intron after exons 3 is one FRT site, an engrailed 2 splice acceptor sequence, an EGFP and cre/ERT2 expression cassette, and a single Rox remaining after a flanked puromycin resistance cassette removal, and a single loxP site remaining after a flanked exons 4 through 13 removal frin Cpne6. (J:155845)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Cpne6 (mouse) Summary of all recombinase alleles driven by Cpne6. Alliance mouse Cpne6 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Cpne6 Mutation: 44 strains or lines available

References

• Original: J:155845 Wellcome Trust Sanger Institute, Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2010
• All: 2 reference(s)