Gap43^{tm2(EGFP/cre/ERT2)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Gap43^{tm2(EGFP/cre/ERT2)Wtsi}
• Name: growth associated protein 43; targeted mutation 2, Wellcome Trust Sanger Institute
• MGI ID: MGI:5632492
• Synonyms: Gap43^{tm2(EGFP/cre/ERT2)Hmgu}
• Gene: Gap43 Location: Chr16:42068915-42161014 bp, - strand Genetic Position: Chr16, 28.37 cM
• Alliance: Gap43^{tm2(EGFP/cre/ERT2)Wtsi} page

Mutation origin

• Mutant Cell Line: CEPD0084_3_D04
• Germline Transmission: Earliest citation of germline transmission: J:204812
• Parent Cell Line: JM8.N4 (ES Cell)
• Strain of Origin: C57BL/6N
• Project Collection: EUCOMMTOOLS

Mutation description

• Allele Type: Targeted (Inducible, Recombinase, Reporter)
• Inducer: tamoxifen
• Mutation: Insertion
• Gap43^{tm2(EGFP/cre/ERT2)Wtsi} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Gap43 (MGI:95639)

• Mutation details: According to the allele molecular image presented by the International Knockout Mouse Consortium, this allele has one FRT site, an engrailed 2 splice acceptor sequence, an EGFP and cre/ERT2 expression cassette, and a neomycin resistance cassette inserted in the intron between exons 1 and 2. A single loxP site is inserted in intron 2. (J:155845)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Gap43 (mouse) Summary of all recombinase alleles driven by Gap43. Alliance mouse Gap43 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Gap43 Mutation: 27 strains or lines available

References

• Original: J:155845 Wellcome Trust Sanger Institute, Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2010
• All: 2 reference(s)