Hipk4tm1b(KOMP)Mbp
Targeted Allele Detail
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Symbol: |
Hipk4tm1b(KOMP)Mbp |
Name: |
homeodomain interacting protein kinase 4; targeted mutation 1b, Mouse Biology Program, UC Davis |
MGI ID: |
MGI:5632532 |
Synonyms: |
Hipk4- |
Gene: |
Hipk4 Location: Chr7:27222692-27230600 bp, + strand Genetic Position: Chr7, 15.92 cM
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Alliance: |
Hipk4tm1b(KOMP)Mbp page
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IMPC: |
Hipk4 gene page |
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Mutant Cell Line: |
DEPD0005_5_G07 |
Germline Transmission: |
Earliest citation of germline transmission:
J:204739
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Parent Cell Line: |
JM8A1.N3 (ES Cell)
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Strain of Origin: |
C57BL/6N-Atm1Brd
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Project Collection: |
KOMP-CSD
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutations: |
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Insertion, Intragenic deletion
Vector: L1L2_Bact_P
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Mutation details: Cre-mediated excision of the parental Hipk4tm1a(KOMP)Mbp allele resulted in the removal of the promoter-driven neomycin selection cassette and critical exons (exons 2 and 3) leaving behind the inserted lacZ reporter sequence. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. PCR of tail-derived genomic DNA and Western blot analyses of whole testis lysates confirmed the absence of functional gene products in homozygous male mice.
(J:204739, J:290279)
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View phenotypes and curated references for all genotypes (concatenated display).
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Original: |
J:204739 International Knockout Mouse Consortium, MGI download of modified allele data from IKMC and creation of new knockout alleles. Database Download. 2014-2023; |
All: |
5 reference(s) |
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