Tg(Pbsn-Lrp5/Fkbp1a,-luc*)#Dmps
Transgene Detail

Summary

• Symbol: Tg(Pbsn-Lrp5/Fkbp1a,-luc*)#Dmps
• Name: transgene insertion, David M Spencer
• MGI ID: MGI:5633983
• Synonyms: Pro-Cat
• Transgene: Tg(Pbsn-Lrp5/Fkbp1a,-luc*)#Dmps Location: unknown
• Alliance: Tg(Pbsn-Lrp5/Fkbp1a,-luc*)#Dmps page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Tg(Pbsn-Lrp5/Fkbp1a,-luc*)#Dmps expresses 2 genes
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  Not Specified	Fkbp1a
  Not Specified	Lrp5

• Mutation details: The probasin promoter drives prostate epithelium specific expression of the cytoplasmic portion of Lrp5 fused to two tandem AP20187 drug binding domains for chemically induced dimerization and the click beetle red-shifted luciferase gene. (J:206727)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:206727 Carstens JL, et al., FGFR1-WNT-TGF-beta signaling in prostate cancer mouse models recapitulates human reactive stroma. Cancer Res. 2014 Jan 15;74(2):609-20
• All: 1 reference(s)