About   Help   FAQ
Tg(Eno2-APP*Ind,-PSEN1*P267S)#Kakiz
Transgene Detail
Summary
Symbol: Tg(Eno2-APP*Ind,-PSEN1*P267S)#Kakiz
Name: transgene insertion, Akira Kakizuka
MGI ID: MGI:5634331
Synonyms: V717F/P267S
Transgene: Tg(Eno2-APP*Ind,-PSEN1*P267S)#Kakiz  Location: unknown  
Alliance: Tg(Eno2-APP*Ind,-PSEN1*P267S)#Kakiz page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsTwo transgenes, one expressing a FLAG-tagged beta-c-terminal fragment of human APP with the Indiana mutation (V717F), and another with an HA-tagged full-length presenilin with the P267S mutation, both under the control of the neuron-specific enolase promoter were coinjected to generate the transgenic mice. The pound symbol (#) is used when line is not specified and/or lines are pooled. (J:212692)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:212692 Sasaoka N, et al., Long-term oral administration of hop flower extracts mitigates Alzheimer phenotypes in mice. PLoS One. 2014;9(1):e87185
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
10/29/2024
MGI 6.24
The Jackson Laboratory