Tg(EIF1AX-Lin28a)#Gqda
Transgene Detail

Summary

• Symbol: Tg(EIF1AX-Lin28a)#Gqda
• Name: transgene insertion, George Q Daley
• MGI ID: MGI:5634777
• Synonyms: LSL-Lin28a
• Transgene: Tg(EIF1AX-Lin28a)#Gqda Location: unknown
• Alliance: Tg(EIF1AX-Lin28a)#Gqda page

Transgene origin

• Germline Transmission: Earliest citation of germline transmission: J:211179
• Parent Cell Line: v6.5 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Transgene description

• Transgene Type: Transgenic (Conditional ready, Inserted expressed sequence)
• Mutation: Insertion
• Tg(EIF1AX-Lin28a)#Gqda expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Lin28a (MGI:1890546)

• Mutation details: The human EIF1AX promoter is followed by a lox-stop-lox cassette and a mouse Lin28a open reading frame with a Flag tag. (J:211179)

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:211179 Urbach A, et al., Lin28 sustains early renal progenitors and induces Wilms tumor. Genes Dev. 2014 May 1;28(9):971-82
• All: 2 reference(s)