Cuedc2^tm1Qxia
Targeted Allele Detail

Summary

• Symbol: Cuedc2^tm1Qxia
• Name: CUE domain containing 2; targeted mutation 1, Qing Xia
• MGI ID: MGI:5635142
• Gene: Cuedc2 Location: Chr19:46318251-46327141 bp, - strand Genetic Position: Chr19, 38.81 cM, cytoband D1
• Alliance: Cuedc2^tm1Qxia page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:211782
• Parent Cell Line: iTL BA1 (ES Cell)
• Strain of Origin: (C57BL/6NTac x 129S6/SvEvTac)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: LoxP-flanked exons 2-9 were removed following cre-mediated recombination. Southern blot analysis confirmed absence of RNA expression. (J:211782)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cuedc2 Mutation: 21 strains or lines available

References

• Original: J:211782 Chen Y, et al., Dysregulation of the MiR-324-5p-CUEDC2 Axis Leads to Macrophage Dysfunction and Is Associated with Colon Cancer. Cell Rep. 2014 Jun 26;7(6):1982-93
• All: 2 reference(s)