Heg1^{tm1.1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Heg1^{tm1.1(KOMP)Vlcg}
• Name: heart development protein with EGF-like domains 1; targeted mutation 1.1, Velocigene
• MGI ID: MGI:5635160
• Gene: Heg1 Location: Chr16:33504754-33591946 bp, + strand Genetic Position: Chr16, 24.17 cM
• Alliance: Heg1^{tm1.1(KOMP)Vlcg} page
• IMPC: Heg1 gene page

Mutation origin

• Mutant Cell Line: 13548A-D3
• Germline Transmission: Earliest citation of germline transmission: J:188991
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 47098bp between positions 33684701-33731798 of Chromosome 16 (Genome Build37) and subsequent Cre-mediated excision deleted the neomycin selection cassette. (J:136110, J:188991)

Expression

In Mice Carrying this Mutation:

51 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Heg1 Mutation: 56 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 4 reference(s)