Ip6k2tm1.1Snyd
Targeted Allele Detail
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Symbol: |
Ip6k2tm1.1Snyd |
Name: |
inositol hexaphosphate kinase 2; targeted mutation 1.1, Solomon Snyder |
MGI ID: |
MGI:5635272 |
Synonyms: |
Ip6k2- |
Gene: |
Ip6k2 Location: Chr9:108660995-108683536 bp, + strand Genetic Position: Chr9, 59.63 cM, cytoband F2
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Alliance: |
Ip6k2tm1.1Snyd page
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Germline Transmission: |
Earliest citation of germline transmission:
J:212482
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A loxP site was inserted upstream of exon 6. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 6. Cre-mediated recombination removed exon 6 and the selection cassette. Western blot analysis confirmed the absence of protein expression in mouse embryonic fibroblasts.
(J:212482)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Ip6k2 Mutation: |
26 strains or lines available
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Original: |
J:212482 Rao F, et al., Inositol pyrophosphates mediate the DNA-PK/ATM-p53 cell death pathway by regulating CK2 phosphorylation of Tti1/Tel2. Mol Cell. 2014 Apr 10;54(1):119-32 |
All: |
4 reference(s) |
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