Tg(Ctgf-cre)1Aibs
Transgene Detail

Summary

• Symbol: Tg(Ctgf-cre)1Aibs
• Name: transgene insertion 1, Ed Lein
• MGI ID: MGI:5635429
• Synonyms: Ctgf-Tg1-Cre
• Transgene: Tg(Ctgf-cre)1Aibs Location: unknown
• Alliance: Tg(Ctgf-cre)1Aibs page

Transgene origin

• Strain of Origin: (C57BL/6 x C3H)F1 x C57BL/6

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Ctgf-cre)1Aibs expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Ccn2 (MGI:95537)

• Mutation details: The 189 kb C57BL/6J mouse bacterial artificial chromosome (BAC) RP23-257E12, containing the entire Ctgf locus (and other genes), was modified by targeting a Cre recombinase coding sequence (the CreERT2 sequence modified back to encode the normal Cre recombinase gene), SV40 polyA signal, and frt-flanked neomycin cassette to the ATG start site of the Ctgf locus. The targeted BAC sequences were further modified using FLP recombination to remove the selection cassette and linearized to remove its original vector backbone. Cre expression is directed to cortex and hippocampus by the Ctgf promoter/enhancer regions within the BAC transgene. (J:146821)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Ccn2 (mouse) Summary of all recombinase alleles driven by Ccn2. Alliance mouse Ccn2 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:220523 Harris JA, et al., Anatomical characterization of Cre driver mice for neural circuit mapping and manipulation. Front Neural Circuits. 2014;8:76
• All: 2 reference(s)