T2dm4sa^SM/J
QTL Variant Detail

Summary

• QTL variant: T2dm4sa^SM/J
• Name: type 2 diabetes mellitus 4 in SMXA RI mice; SM/J
• MGI ID: MGI:5635834
• QTL: T2dm4sa Location: Chr6:83690851-146954059 bp Genetic Position: Chr6, Syntenic

Variant origin

• Strain of Specimen: SM/J

Variant description

• Allele Type: QTL

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:145482

An (A/J x SM.A-T2dm2sa) F2 intercross fed a high-fat diet were informative in mapping diabetogenic QTLs to mouse Chromosomes 6 and 11. T2dm4sa, mapped to mouse Chromosome 6 near D6Mit287 and between D6Mit8 and D6Mit373 with a LOD of 5.2. T2dm5sa mapped to mouse Chromosome 11 between D11Mit8 and D11Mit10 with a peak at D11Mit122 with a LOD of 4.0

References

• Original: J:145482 Hada N, et al., Quantitative trait loci for impaired glucose tolerance in nondiabetic SM/J and A/J mice. Physiol Genomics. 2008 Sep 17;35(1):65-74
• All: 1 reference(s)