Tg(Rr437-cre)#Hmd
Transgene Detail

Summary

• Symbol: Tg(Rr437-cre)#Hmd
• Name: transgene insertion, Hiroshi Hamada
• MGI ID: MGI:5636045
• Synonyms: Pitx2-Cre, Tg(Rr437-cre)#Hmd
• Transgene: Tg(Rr437-cre)#Hmd Location: unknown
• Alliance: Tg(Rr437-cre)#Hmd page

Transgene origin

• Strain of Origin: C57BL/6J X (C57BL/6 x C3H)F1

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Rr437-cre)#Hmd expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Pitx2 (MGI:109340)

• Mutation details: The transgene contains a 1.3 kb fragment of the mouse promoter, a cre recombinase gene and a 17 kb fragment containing exons 1c, 4 and 5, as well as the intronic enhancer ASE and 3' flanking region of, Pitx2. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:128475)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Pitx2 (mouse) Summary of all recombinase alleles driven by Pitx2. Comparative matrix view of recombinase activities Alliance mouse Pitx2 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

The transgene was first introduced into Pitx2 heterozygotes.

References

• Original: J:128475 Shiratori H, et al., Conserved regulation and role of Pitx2 in situs-specific morphogenesis of visceral organs. Development. 2006 Aug;133(15):3015-25
• All: 6 reference(s)