Atp2b2^dfw-i5
Chemically induced Allele Detail

Summary

• Symbol: Atp2b2^dfw-i5
• Name: ATPase, Ca++ transporting, plasma membrane 2; deaf waddler i5
• MGI ID: MGI:5636635
• Synonyms: Line 70
• Gene: Atp2b2 Location: Chr6:113720803-114019574 bp, - strand Genetic Position: Chr6, 52.85 cM
• Alliance: Atp2b2^dfw-i5 page

Mutation origin

• Strain of Origin: DBA/2J

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced an A to T point mutation that introduces a premature stop codon. Western blot analysis confirmed the absence of protein expression. (J:220660)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atp2b2 Mutation: 66 strains or lines available

References

• Original: J:220660 Watson CJ, et al., A new Atp2b2 deafwaddler allele, dfw(i5), interacts strongly with Cdh23 and other auditory modifiers. Hear Res. 2013 Oct;304:41-8
• All: 2 reference(s)