Eif3b^{Gt(GT529)Skmz}
Gene trapped Allele Detail

Summary

• Symbol: Eif3b^{Gt(GT529)Skmz}
• Name: eukaryotic translation initiation factor 3, subunit B; gene trap mutation GT529, Kazuhisa Sekimizu
• MGI ID: MGI:5636799
• Synonyms: p116^-
• Gene: Eif3b Location: Chr5:140405083-140429115 bp, + strand Genetic Position: Chr5, 78.97 cM
• Alliance: Eif3b^{Gt(GT529)Skmz} page

Mutation origin

• Mutant Cell Line: GT529
• Germline Transmission: Earliest citation of germline transmission: J:220883
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: A gene trap vector (containing Bgal and Neo) inserted into intron 1 of the gene, disrupting the normal function (null mutation). Homozygosity is early embryonic lethal. (J:220883)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Eif3b Mutation: 31 strains or lines available

References

• Original: J:220883 Koyanagi-Katsuta R, et al., Embryonic lethality of mutant mice deficient in the p116 gene. J Biochem. 2002 Jun;131(6):833-7
• All: 1 reference(s)