Pex10^m1Nisw
Chemically induced Allele Detail

Summary

• Symbol: Pex10^m1Nisw
• Name: peroxisomal biogenesis factor 10; mutation 1, Lee Niswander
• MGI ID: MGI:5638060
• Synonyms: Pex10^CY
• Gene: Pex10 Location: Chr4:155151487-155156863 bp, + strand Genetic Position: Chr4, 86.17 cM
• Alliance: Pex10^m1Nisw page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU induced a single base pair change from G to A, that results in the amino acid substitution of a cysteine for tyrosine at position 294 (C294Y), which disrupts the second zinc RING finger binding domain. (J:216140)

Expression

In Mice Carrying this Mutation:	18 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pex10 Mutation: 15 strains or lines available

References

• Original: J:216140 Hanson MG, et al., Peripheral nervous system defects in a mouse model for peroxisomal biogenesis disorders. Dev Biol. 2014 Nov 1;395(1):84-95
• All: 1 reference(s)