Slc12a5^tm2Hsav
Targeted Allele Detail

Summary

• Symbol: Slc12a5^tm2Hsav
• Name: solute carrier family 12, member 5; targeted mutation 2, Harri Savilahti
• MGI ID: MGI:5638435
• Synonyms: KCC2^_, KCC2^nu, KCC2^null
• Gene: Slc12a5 Location: Chr2:164802766-164841651 bp, + strand Genetic Position: Chr2, 85.28 cM, cytoband G2-G3
• Alliance: Slc12a5^tm2Hsav page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101079
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A floxed neo-mu cassette was inserted 14 bp downstream from the 5'end of exon 4 that contains a mini-Mu transposon. (J:127091)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc12a5 Mutation: 45 strains or lines available

References

• Original: J:127091 Vilen H, et al., Construction of gene-targeting vectors: a rapid Mu in vitro DNA transposition-based strategy generating null, potentially hypomorphic, and conditional alleles. Transgenic Res. 2001;10(1):69-80
• All: 7 reference(s)