Atp6ap1^tm1Mhzh
Targeted Allele Detail

Summary

• Symbol: Atp6ap1^tm1Mhzh
• Name: ATPase, H+ transporting, lysosomal accessory protein 1; targeted mutation 1, Ming H Zheng
• MGI ID: MGI:5638540
• Synonyms: Ac45-Flox^Neo
• Gene: Atp6ap1 Location: ChrX:73340753-73348297 bp, + strand Genetic Position: ChrX, 37.96 cM
• Alliance: Atp6ap1^tm1Mhzh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:220934
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 3. A neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 4. (J:220934)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atp6ap1 Mutation: 9 strains or lines available

References

• Original: J:220934 Qin A, et al., Versatile roles of V-ATPases accessory subunit Ac45 in osteoclast formation and function. PLoS One. 2011;6(11):e27155
• All: 1 reference(s)