Ccr8^tm1Yiw
Targeted Allele Detail

Summary

• Symbol: Ccr8^tm1Yiw
• Name: C-C motif chemokine receptor 8; targeted mutation 1, Yoichiro Iwakura
• MGI ID: MGI:5638754
• Synonyms: Ccr8^tm1Tdoh
• Gene: Ccr8 Location: Chr9:119921199-119923972 bp, + strand Genetic Position: Chr9, 71.39 cM, cytoband F4
• Alliance: Ccr8^tm1Yiw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:215014
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Not Specified
• Mutation details: A neomycin resistance cassette replaced most of exon 2. PCR confirmed the absence of transcript expression in T cells. (J:230918)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Ccr8 Mutation: 41 strains or lines available

References

• Original: J:215014 Oshio T, et al., Chemokine receptor CCR8 is required for lipopolysaccharide-triggered cytokine production in mouse peritoneal macrophages. PLoS One. 2014;9(4):e94445
• All: 3 reference(s)