Bcl9^tm1.1Kba
Targeted Allele Detail

Summary

• Symbol: Bcl9^tm1.1Kba
• Name: B cell CLL/lymphoma 9; targeted mutation 1.1, Konrad Basler
• MGI ID: MGI:5638790
• Synonyms: Bcl9^deltaHD1
• Gene: Bcl9 Location: Chr3:97110978-97205233 bp, - strand Genetic Position: Chr3, 42.04 cM, cytoband F2
• Alliance: Bcl9^tm1.1Kba page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:213694
• Parent Cell Line: iTL BA1 (ES Cell)
• Strain of Origin: (C57BL/6NTac x 129S6/SvEvTac)F1

Mutation description

• Allele Type: Targeted (Not Applicable)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 6 and 7 were replaced with a fused exon 6-7 lacking the HD1 domain and an FRT and loxP flanked neo cassette was inserted intron 7 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:213694)

Expression

In Mice Carrying this Mutation:

4 assay results 1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bcl9 Mutation: 47 strains or lines available

References

• Original: J:213694 Cantu C, et al., Pax6-dependent, but beta-catenin-independent, function of Bcl9 proteins in mouse lens development. Genes Dev. 2014 Sep 1;28(17):1879-84
• All: 4 reference(s)