Pygo2^tm2Kba
Targeted Allele Detail

Summary

• Symbol: Pygo2^tm2Kba
• Name: pygopus 2; targeted mutation 2, Konrad Basler
• MGI ID: MGI:5638877
• Gene: Pygo2 Location: Chr3:89337521-89342435 bp, + strand Genetic Position: Chr3, 39.12 cM
• Alliance: Pygo2^tm2Kba page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:213694
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: An FRT flanked neomycin resistance cassette with a 5' loxP site was inserted upstream of exon 3. A loxP site was inserted downstream of the PHD finger coding sequence in exon 3. (J:213694)

Expression

In Mice Carrying this Mutation:

2 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pygo2 Mutation: 24 strains or lines available

References

• Original: J:213694 Cantu C, et al., Pax6-dependent, but beta-catenin-independent, function of Bcl9 proteins in mouse lens development. Genes Dev. 2014 Sep 1;28(17):1879-84
• All: 4 reference(s)