Card11^m3Btlr
Chemically induced Allele Detail

Summary

• Symbol: Card11^m3Btlr
• Name: caspase recruitment domain family, member 11; mutation 3, Bruce Beutler
• MGI ID: MGI:5640756
• Synonyms: hubei
• Gene: Card11 Location: Chr5:140858745-140986337 bp, - strand Genetic Position: Chr5, 79.42 cM
• Alliance: Card11^m3Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: The mutation is an A to G transition at base pair 140,906,767 (v38) on chromosome 5, or base pair 93,830 in the GenBank genomic region NC_000071. The mutation corresponds to residue 863 in the mRNA sequence NM_175362 within exon 5 of 25 total exons. The mutation results in a tyrosine (Y) to cysteine (C) substitution at position 181 (Y181C) (J:221487)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Card11 Mutation: 59 strains or lines available

References

• Original: J:221487 Zeng M, et al., Mutagenetix entry for hubei. MGI Direct Data Submission. 2015
• All: 1 reference(s)