Dock2^m4Btlr
Chemically induced Allele Detail

Summary

• Symbol: Dock2^m4Btlr
• Name: dedicator of cyto-kinesis 2; mutation 4, Bruce Beutler
• MGI ID: MGI:5640757
• Synonyms: liaoning
• Gene: Dock2 Location: Chr11:34176815-34674719 bp, - strand Genetic Position: Chr11, 19.68 cM, cytoband A5
• Alliance: Dock2^m4Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: The mutation is an A to G transition at base pair 34,708,793 (v38) on chromosome 11, or base pair 75,113 in the GenBank genomic region NC_000077. The mutation corresponds to residue 1,040 in the NM_033374 mRNA sequence within exon 10 of 52 total exons. The mutation results in an arginine (R) to glycine (G) substitution at position 320 (R320G). (J:221486)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dock2 Mutation: 143 strains or lines available

References

• Original: J:221486 Zeng M, et al., Mutagenetix entry for liaoning. MGI Direct Data Submission. 2015
• All: 1 reference(s)