Mapk3^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Mapk3^m1Btlr
• Name: mitogen-activated protein kinase 3; mutation 1, Bruce Beutler
• MGI ID: MGI:5640774
• Synonyms: wabasha
• Gene: Mapk3 Location: Chr7:126358798-126364988 bp, + strand Genetic Position: Chr7, 69.25 cM
• Alliance: Mapk3^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: The mutation is an A to T transversion at base pair 126,763,512 (v38) on chromosome 7, or base pair 4,114 in the GenBank genomic region NC_000073. The mutation corresponds to residue 681 in the mRNA sequence NM_011952 within exon 4 of 9 total exons. The mutation results in substitution of lysine (K) 221 to a premature stop codon. (J:221481)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mapk3 Mutation: 26 strains or lines available

References

• Original: J:221481 Shi X, et al., Mutagenetix entry for wabasha. MGI Direct Data Submission. 2015
• All: 1 reference(s)