Rac2^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Rac2^m1Btlr
• Name: Rac family small GTPase 2; mutation 1, Bruce Beutler
• MGI ID: MGI:5640784
• Synonyms: bingo
• Gene: Rac2 Location: Chr15:78443369-78456983 bp, - strand Genetic Position: Chr15, 37.57 cM
• Alliance: Rac2^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: The mutation is an A to G transition at base pair 78,564,968 (v38) on chromosome 15, or base pair 7,816 in the GenBank genomic region NC_000081. The mutation corresponds to residue 481 in the mRNA sequence NM_009008 within exon 5 of 7 total exons. The mutation results in a threonine (T) to alanine (A) substitution at position 115 (T115A). (J:221478)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rac2 Mutation: 17 strains or lines available

References

• Original: J:221478 Choi JH, et al., Mutagenetix entry for bingo. MGI Direct Data Submission. 2015
• All: 1 reference(s)