Ccr7^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Ccr7^m1Btlr
• Name: C-C motif chemokine receptor 7; mutation 1, Bruce Beutler
• MGI ID: MGI:5640785
• Synonyms: lanzhou
• Gene: Ccr7 Location: Chr11:99035025-99045903 bp, - strand Genetic Position: Chr11, 62.92 cM, cytoband D
• Alliance: Ccr7^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: The mutation is a T to A transversion at base pair 99,145,277 (v38) on chromosome 11, or base pair 9,801 in the GenBank genomic region NC_000077. The mutation corresponds to residue 897 in the mRNA sequence NM_007719 within exon 3 of 3 total exons. The mutation results in an isoleucine (L) to lysine (K) substitution at position 273 (I273K). (J:221477)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ccr7 Mutation: 29 strains or lines available

References

• Original: J:221477 Zeng M, et al., Mutagenetix entry for lanzhou. MGI Direct Data Submission. 2015
• All: 1 reference(s)