Socs2^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Socs2^m1Btlr
• Name: suppressor of cytokine signaling 2; mutation 1, Bruce Beutler
• MGI ID: MGI:5640786
• Synonyms: samson
• Gene: Socs2 Location: Chr10:95221224-95253042 bp, - strand Genetic Position: Chr10, 49.35 cM
• Alliance: Socs2^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: The mutation is a G to T transversion at base pair 95,413,081 (v38) on chromosome 10, or base pair 4,173 in the GenBank genomic region NC_000076. The mutation corresponds to residue 631 in the mRNA sequence NM_145223 within exon 3 of 3 total exons. The mutated nucleotide converts glutamine 57 to a stop codon. (J:221476)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Socs2 Mutation: 24 strains or lines available

References

• Original: J:221476 Chen Z, et al., Mutagenetix entry for samson. MGI Direct Data Submission. 2015
• All: 1 reference(s)