Malt1^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Malt1^m1Btlr
• Name: MALT1 paracaspase; mutation 1, Bruce Beutler
• MGI ID: MGI:5640788
• Synonyms: mousebird
• Gene: Malt1 Location: Chr18:65564010-65612138 bp, + strand Genetic Position: Chr18, 38.56 cM
• Alliance: Malt1^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: The mutation is a T-to-A transversion at base pair 65,475,260 (GRCm38) on chromosome 18, or base pair 44,325 in the GenBank genomic region NC_000084. The mutation corresponds to nucleotide two within the donor splice site of intron 15. The effect of the mutation at the cDNA and protein level has not been tested, but the mutation is predicted to result in skipping of the 126-base pair exon 15 (out of 16 total exons). Skipping of exon 15 would cause an in-frame deletion of amino acids 635-676. (J:221474)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Malt1 Mutation: 35 strains or lines available

References

• Original: J:221474 Wang KW, et al., Mutagenetix entry for mousebird. MGI Direct Data Submission. 2015
• All: 2 reference(s)