Sumo2^tm1Weiy
Targeted Allele Detail

Summary

• Symbol: Sumo2^tm1Weiy
• Name: small ubiquitin-like modifier 2; targeted mutation 1, Wei Yang
• MGI ID: MGI:5641883
• Synonyms: Sumo2^-
• Gene: Sumo2 Location: Chr11:115413935-115427056 bp, - strand Genetic Position: Chr11, 80.84 cM
• Alliance: Sumo2^tm1Weiy page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:217019
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: Exon 1 was disrupted by in-frame insertion of two premature stop codons and a neomycin resistance cassette downstream of the ATG codon. Whole-mount in situ hybridization analysis of homozygous mutant embryos confirmed that this is a functionally null allele. (J:217019)

Expression

In Mice Carrying this Mutation:	65 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Sumo2 Mutation: 16 strains or lines available

References

• Original: J:217019 Wang L, et al., SUMO2 is essential while SUMO3 is dispensable for mouse embryonic development. EMBO Rep. 2014 Aug;15(8):878-85
• All: 3 reference(s)