Tg(CD2-Il23r)2Cdon
Transgene Detail
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Symbol: |
Tg(CD2-Il23r)2Cdon |
Name: |
transgene insertion 2, Chen Dong |
MGI ID: |
MGI:5642079 |
Synonyms: |
IL-23R Tg |
Transgene: |
Tg(CD2-Il23r)2Cdon Location: unknown
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Alliance: |
Tg(CD2-Il23r)2Cdon page
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(CD2-Il23r)2Cdon expresses
1 gene
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Mutation details: A transgenic vector was generated with interleukin 23 receptor (Il23r) cDNA, amplified from a T helper (Th) 17 cell pool, followed by polyadenylation signal (polyA), under control of a human CD2 promoter. This construct also contains the CD2 locus control region (LCR) to increase gene expression by preventing the down-modulation of the expressed gene. Line 2 was analyzed.
(J:221933)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Original: |
J:221933 Peng J, et al., IL-23 signaling enhances Th2 polarization and regulates allergic airway inflammation. Cell Res. 2010 Jan;20(1):62-71 |
All: |
1 reference(s) |
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