Rspo3^tm1Arte
Targeted Allele Detail

Summary

• Symbol: Rspo3^tm1Arte
• Name: R-spondin 3; targeted mutation 1, TaconicArtemis
• MGI ID: MGI:5643687
• Synonyms: Rspo3^f
• Gene: Rspo3 Location: Chr10:29329102-29411863 bp, - strand Genetic Position: Chr10, 16.64 cM, cytoband A4
• Alliance: Rspo3^tm1Arte page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:214093
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 1. A neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 1. (J:214093)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rspo3 Mutation: 13 strains or lines available

References

• Original: J:214093 Cambier L, et al., Nkx2-5 regulates cardiac growth through modulation of Wnt signaling by R-spondin3. Development. 2014 Aug;141(15):2959-71
• All: 7 reference(s)