Dnd1^tm1Na
Targeted Allele Detail

Summary

• Symbol: Dnd1^tm1Na
• Name: DND microRNA-mediated repression inhibitor 1; targeted mutation 1, Joseph H Nadeau
• MGI ID: MGI:5644313
• Synonyms: Dnd1^KO
• Gene: Dnd1 Location: Chr18:36896724-36899267 bp, - strand Genetic Position: Chr18, 19.46 cM
• Alliance: Dnd1^tm1Na page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:221231
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neomycin resistance cassette replaced exon 1, 2 and part of exon 3. (J:221231)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dnd1 Mutation: 16 strains or lines available

References

• Original: J:221231 Zechel JL, et al., Contrasting effects of Deadend1 (Dnd1) gain and loss of function mutations on allelic inheritance, testicular cancer, and intestinal polyposis. BMC Genet. 2013;14:54
• All: 1 reference(s)