Gipc1^tm1.1Mhsi
Targeted Allele Detail

Summary

• Symbol: Gipc1^tm1.1Mhsi
• Name: GIPC PDZ domain containing family, member 1; targeted mutation 1.1, Michael Simons
• MGI ID: MGI:5644333
• Synonyms: gipc1^flox
• Gene: Gipc1 Location: Chr8:84379306-84391323 bp, + strand Genetic Position: Chr8, 40.22 cM, cytoband C3
• Alliance: Gipc1^tm1.1Mhsi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:221554
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S1/SvImJ

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2. An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted downstream of exon 2. Flp-mediated recombination removed the selection cassette and left exon 2 floxed. (J:221554)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gipc1 Mutation: 42 strains or lines available

References

• Original: J:221554 Moraes F, et al., Endothelial cell-dependent regulation of arteriogenesis. Circ Res. 2013 Oct 12;113(9):1076-86
• All: 2 reference(s)