Gpr174^tm1Cys
Targeted Allele Detail

Summary

• Symbol: Gpr174^tm1Cys
• Name: G protein-coupled receptor 174; targeted mutation 1, Jason G Cyster
• MGI ID: MGI:5644336
• Gene: Gpr174 Location: ChrX:106299484-106340375 bp, + strand Genetic Position: ChrX, 47.48 cM
• Alliance: Gpr174^tm1Cys page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:222307
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: An in-frame dTomato reporter gene and floxed neomycin resistance cassette replaced the open reading frame. (J:222307)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gpr174 Mutation: 5 strains or lines available

References

• Original: J:222307 Barnes MJ, et al., The lysophosphatidylserine receptor GPR174 constrains regulatory T cell development and function. J Exp Med. 2015 Jun 29;212(7):1011-20
• All: 1 reference(s)