Rbm8a^tm1Dlsi
Targeted Allele Detail

Summary

• Symbol: Rbm8a^tm1Dlsi
• Name: RNA binding motif protein 8a; targeted mutation 1, Debra L Silver
• MGI ID: MGI:5644432
• Synonyms: Rbm8a^loxp
• Gene: Rbm8a Location: Chr3:96537249-96541107 bp, + strand Genetic Position: Chr3, 41.93 cM, cytoband H3
• Alliance: Rbm8a^tm1Dlsi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:221648
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exons 2-5 were flanked by loxP sites with Frt-neo-Frt cassette inserted before the second loxP site in intron 5. (J:221648)

Expression

In Mice Carrying this Mutation:	19 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rbm8a Mutation: 7 strains or lines available

References

• Original: J:221648 Mao H, et al., Rbm8a haploinsufficiency disrupts embryonic cortical development resulting in microcephaly. J Neurosci. 2015 May 6;35(18):7003-18
• All: 2 reference(s)