Nabp1^tm1Kkha
Targeted Allele Detail

Summary

• Symbol: Nabp1^tm1Kkha
• Name: nucleic acid binding protein 1; targeted mutation 1, Kum Kum Khanna
• MGI ID: MGI:5644720
• Synonyms: Ssb2 flneo, Ssb2 floxed/neo
• Gene: Nabp1 Location: Chr1:51505021-51517584 bp, - strand Genetic Position: Chr1, 26.58 cM, cytoband C1
• Alliance: Nabp1^tm1Kkha page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:220670
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: The targeting construct introduced a frt site-flanked neomycin resistance cassette (neo^r) in the first intron and loxP sites upstream of the selection cassette and downstream of exon 2. The selection cassette can be deleted by Flp recombinase, and both neo^r and exon 2 by Cre recombinase. (J:220670)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Nabp1 Mutation: 15 strains or lines available

References

• Original: J:220670 Boucher D, et al., Ssb2/Nabp1 is dispensable for thymic maturation, male fertility, and DNA repair in mice. FASEB J. 2015 Aug;29(8):3326-34
• All: 2 reference(s)