Tamm41^{tm1b(KOMP)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Tamm41^{tm1b(KOMP)Wtsi}
• Name: TAM41 mitochondrial translocator assembly and maintenance homolog; targeted mutation 1b, Wellcome Trust Sanger Institute
• MGI ID: MGI:5644833
• Synonyms: Tam41 null
• Gene: Tamm41 Location: Chr6:114981342-115014837 bp, - strand Genetic Position: Chr6, 53.14 cM, cytoband E3
• Alliance: Tamm41^{tm1b(KOMP)Wtsi} page
• IMPC: Tamm41 gene page

Mutation origin

• Mutant Cell Line: EPD0610_1_H07
• Germline Transmission: Earliest citation of germline transmission: J:94077
• Parent Cell Line: JM8A3.N1 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd
• Project Collection: KOMP-CSD

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: L1L2_Bact_P
• Mutation details: The L1L2_Bact_P cassette was inserted at position 115025851 of Chromosome 6 upstream of exon 4. The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of exon 4. Cre-mediated recombination removed the floxed neo cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. (J:94077)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tamm41 Mutation: 18 strains or lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 1 reference(s)