Smarca4^tm1.1Grc
Targeted Allele Detail

Summary

• Symbol: Smarca4^tm1.1Grc
• Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4; targeted mutation 1.1, Gerald R Crabtree
• MGI ID: MGI:5645479
• Synonyms: Smarca4^Dendra
• Gene: Smarca4 Location: Chr9:21527465-21615526 bp, + strand Genetic Position: Chr9, 7.84 cM
• Alliance: Smarca4^tm1.1Grc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101977
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: Dendra2 sequence derived from BAC bMQ-242m22 was inserted with a loxP-flanked neomycin cassette into the C-terminus of the Smarca4 gene. Cre-mediated recombination removed the floxed neo cassette. Expression is confirmed by Western blot using anti-Brg (SMARCA4) and anti-Dendra2 antibodies. Cells show nuclear fluorescence which can undergo photoswitching. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Smarca4 Mutation: 110 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 1 reference(s)