Tg(ANPEP)861Mmul
Transgene Detail

Summary

• Symbol: Tg(ANPEP)861Mmul
• Name: transgene insertion 861, Mathias Muller
• MGI ID: MGI:5645779
• Synonyms: Tg(APN)861
• Transgene: Tg(ANPEP)861Mmul Location: unknown
• Alliance: Tg(ANPEP)861Mmul page

Transgene origin

• Strain of Origin: ICR

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(ANPEP)861Mmul expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  ANPEP (290)

  Anpep

  (MGI:5000466)

• Mutation details: A human cDNA is expressed under the control of 11-kb of the human 5 gene regulatory sequences. Ten transgenic lines were created (270, 275, 313, 315, 735, 746, 795, 861, 884, and 902). Mouse lines 270 and 861 expressed the highest levels of hAPN mRNA and were studied further. (J:99728)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:99728 Lassnig C, et al., Development of a transgenic mouse model susceptible to human coronavirus 229E. Proc Natl Acad Sci U S A. 2005 Jun 7;102(23):8275-80
• All: 1 reference(s)