Coprs^tm1Efab
Targeted Allele Detail

Summary

• Symbol: Coprs^tm1Efab
• Name: coordinator of PRMT5, differentiation stimulator; targeted mutation 1, Eric Fabbrizio
• MGI ID: MGI:5646193
• Gene: Coprs Location: Chr8:13934794-13940281 bp, - strand Genetic Position: Chr8, 6.41 cM
• Alliance: Coprs^tm1Efab page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:221154
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exons 2-4 were flanked by two loxP sites. Frt-neo-loxP-frt in intron 4 was removed in conditional allele. (J:221154)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Coprs Mutation: 10 strains or lines available

References

• Original: J:221154 Paul C, et al., The Wnt-target gene Dlk-1 is regulated by the Prmt5-associated factor Copr5 during adipogenic conversion. Biol Open. 2015;4(3):312-6
• All: 1 reference(s)